Dying from rabies is extremely rare in the U.S. (1–3 cases annually) but remains a major global issue with ~59,000 annual deaths, mostly in Asia and Africa. While the disease is nearly 100% fatal once symptoms appear, it is almost entirely preventable with prompt medical care (post-exposure prophylaxis).

How common is death from rabies?

Each year, this vaccine-preventable disease is responsible for approximately 59,000 deaths globally. That's approximately one person dying from rabies every 9 minutes. Worldwide, 40% of people infected with rabies are children under the age of 15 years. In the U.S., deaths from rabies are rare.

How long until rabies kills a human?

Once rabies symptoms appear, death typically occurs within 7 to 10 days, usually from respiratory or cardiac failure, as the disease causes fatal brain inflammation (encephalitis); survival after symptoms start is almost unheard of, making immediate treatment after animal exposure critical during the incubation period (days to months) before the virus reaches the brain.

Is 7 days too late for rabies vaccine?

Even if you have been bitten a few days, weeks or months ago, it is never too late to start. The rabies virus can incubate for several years before it causes symptoms. If you wait until you get symptoms, it will be too late – there is no treatment for established rabies …

How rare is rabies now?

In the U.S., around 4,000 animal rabies cases are reported each year, with more than 90% occurring in wildlife like bats, raccoons, skunks, and foxes. This is a big change from the 1960s, when domestic animals, mainly dogs, represented most of the rabies cases.

The Devastating Effects of Rabies

How likely am I to get rabies from a scratch?

Rabies is transmitted through saliva, so fortunately the chances of contracting rabies from a cat scratch are low. The only chance that it might be spread through a scratch is when scratching is accompanied by hissing and biting, which can aerosolize and transmit the virus to another individual.

How quickly will I know if I have rabies?

Rabies symptoms usually appear 1 to 3 months after exposure, but the incubation period can range from a few days to over a year, depending on the bite's location (closer to the brain means faster onset), severity, and the person's age, with early signs like fever, headache, and tingling at the wound site progressing to anxiety, paralysis, and hydrophobia. Prompt washing of the wound and post-exposure prophylaxis (PEP) are critical to prevent the virus from reaching the brain.

Is the rabies shot painful?

Current rabies vaccines are relatively painless and are given in the arm, like a flu or tetanus vaccine. Human Rabies Immune Globulin (HRIG) will be administered around any wound(s) and may be more painful depending on the severity of the wounds. Adverse reactions to rabies vaccine and immune globulin are not common.

How to tell if a dog has rabies?

Symptoms of Rabies In Dogs

1. Barking differently.
2. Excessive drooling.
3. Uncharacteristic aggression, fearfulness or even affection.
4. Overreaction to touch, sound or light.
5. Biting at the site where they were exposed to the virus.

Why can't we cure rabies?

There's no cure for rabies once it's moved to your brain because it's protected by your blood-brain barrier. Your blood-brain barrier is a layer between your brain and the blood vessels in your head.

Is rabies 100% fatal in dogs?

All mammals are susceptible to rabies. Rabies is a deadly disease caused by a virus that attacks the nervous system. Once the outward signs of the disease appear, rabies is nearly always fatal.

How many people died from rabies in the US in 2025?

"Fortunately, there are only a handful of human rabies cases reported annually, and there is an effective vaccine that can be given to patients after an at-risk animal bite." Six people have died from rabies in the U.S. over the last year, with two of those deaths in 2025, the CDC spokesperson told Fox News Digital.

How common is rabies in dogs?

Although dog rabies remains common in many countries, the canine strain of rabies has been eliminated from the United States and dogs make up only about 1% of rabid animals reported each year in the U.S.

What are the first signs of rabies in humans?

Early signs of rabies in humans are often flu-like (fever, headache, weakness, discomfort) and include unusual tingling, itching, or pain at the bite site, lasting several days before more severe neurological symptoms like anxiety, confusion, and hallucinations develop as the virus reaches the brain.
 

Is it rare to get rabies from a cat bite?

This doesn't mean you can get rabies if a cat licks or drools on you. The saliva needs to come in contact with a mucus membrane or broken skin. Animals most commonly transmit rabies to humans through bites. It is possible for a human to get rabies from an animal scratch, but it's very rare.

When is it too late to treat rabies?

There have been instances when a person did not start rabies shots for months after an exposure because the exposure was never suspected. Once a person develops rabies symptoms it is too late to vaccinate against rabies!

Why is rabies 99% fatal?

As the virus moves to the central nervous system, progressive and fatal inflammation of the brain and spinal cord develops. Clinical rabies in people can be managed but very rarely cured, and not without severe neurological deficits.

What happens if you don't vaccinate for rabies?

Failing to vaccinate your pet in accordance with local or federal mandates can result in fines or other legal penalties. In the event of dog bites, state laws may also treat your pet differently depending on their vaccination status, as we covered in our discussion on rabies.

Does rabies make you want to bite people?

Virus interacts with muscle receptors

Dogs have more than 20,000 genes with sophisticated immune and central nervous systems.” “Yet this virus can reprogram a dog's behavior so it loses fear, becomes aggressive and bites, which allows the virus to spread through the dog's saliva.”

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