I was just in a recent conversation with someone about arthritis pain in dogs as one of our dogs who passed away at almost 17 years of age had dysplastic joints in both the rear and the front. I know many people who give glucosamine and perhaps go that extra mile to getting shots from their veterinarian. Dixie's joints were worse than what these things could handle, though both very good solutions.\n\nWhat I found that worked for her is the human vitamin supplement, SamE. Just a standard over the counter pill that can be had (albeit expensive) at any local Walmart or Meijer, etc. She was depressed and struggling to get outside to pee so she'd just potty in the house. A very smart border collie who basically housetrained herself in a matter of days at only six weeks old when adopted from the county animal control and being the alpha of our pack who I bragged potty trained our puppies for us (I used to raise/show dogs) by rolling them like little bowling balls to the door if they dared pee on the floor. She traumatized them enough they would race for the door when they had to go so she wouldn't do that. We called her Grandma Dixie (she was spayed at a young age but still motherly). So to have her do this was heart wrenching. In just TWO DAYS of giving her the SamE supplement, she was happier (it also has serotonin for mood lifting) and was walking so much better. In a weeks time she actually had her tail wagging and just limping a bit. She may have been struggling but she was still getting joy from life and enjoying being part of our family. Eventually, she was lovingly euthanized and she now resides in our family memorial garden. We still bring her ice cream cones. But the SamE gave us about two more years with her that we wouldn't have had the heart to put her through if we felt she was suffering.\n\nI'm no vet so not telling anyone to use this but sharing information as I sit missing our girl so that maybe you can consider it to the point of asking your veterinarian for his/her opinion to see if it may help other dogs and families as well.