Rabies is most common in Asia and Africa, which account for up to 95% of the estimated 59,000 annual human deaths worldwide. It is primarily a disease of poor, rural communities, with 99% of human cases resulting from bites by infected dogs.

Where is rabies most common in humans?

Up to 95% of human deaths occur in Africa and Asia where dog rabies is poorly controlled and disproportionately affects poor rural communities where control programmes and access to appropriate post-exposure prophylaxis (PEP) is limited or non-existent.

Is rabies 100% preventable?

Among animals, there were 3,579 reported cases of rabies in the U.S. in 2022. You can help prevent rabies infections by vaccinating your animals and keeping them away from wildlife that can spread the disease. Rabies is 100% preventable.

Does rabies exist outside of America?

Rabies is known to exist on every continent except Antarctica, and overseas travel to high-risk areas can increase the risk of rabies exposure. In fact, rabies causes 59,000 deaths in 150 countries each year, with 95% of cases occurring in Africa and Asia, mostly among rural poor populations.

Which country has no rabies?

Among countries outside the EU, Andorra, Iceland, Liechtenstein, Monaco, San Marino, Norway (mainland), Switzerland and the United Kingdom are free of terrestrial rabies, according to the Centers for Disease Control and Prevention.

Rabies: One of the Most Deadly Viruses

What animals cannot get rabies?

Birds, fish, reptiles (snakes, turtles, lizards), amphibians (frogs, salamanders), and insects cannot get or spread rabies, as it only affects mammals; however, while small rodents like mice, squirrels, and chipmunks rarely get rabies, they usually don't transmit it, but opossums and large rodents (woodchucks) can, and it's crucial to vaccinate pets and livestock against this virus, notes.
 

Where to go if bit by raccoon?

You should go to the emergency room right away, or if you are unable to get there yourself, call 911 for assistance. Raccoon bites and scratches can spread rabies, a viral disease that can be fatal. Fortunately, rabies can be prevented if post-exposure shots are administered quickly.

Are we close to a cure for rabies?

Will there be a cure for rabies? Researchers are currently working on creating a cure for rabies. Once rabies reaches the brain, it is impossible to treat. But there are some medications that have already shown hope in animal studies.

Why does Hawaii have no rabies?

Hawaii is the only rabies-free U.S. state because of its strict, long-standing animal quarantine laws established in 1912, preventing infected animals from entering, along with its natural geographic isolation as an island chain, which limits the introduction of the virus from wild populations. While a rabid bat was once found (likely arriving by ship), Hawaii's rigorous quarantine for dogs, cats, and other carnivores ensures the disease doesn't establish itself in the local animal population, protecting both pets and people.
 

What state does not require rabies vaccines?

Per the State of Hawaii, Department of Health: "Hawaii is the only state in the United States that is free of rabies and all dogs and cats entering the state must follow import rabies quarantine requirements. Cases of the disease in Hawaii have all been infected through exposures outside of the state."

What are the first signs of rabies in humans?

Early signs of rabies in humans are often flu-like (fever, headache, weakness, discomfort) and include unusual tingling, itching, or pain at the bite site, lasting several days before more severe neurological symptoms like anxiety, confusion, and hallucinations develop as the virus reaches the brain.
 

What animal is most likely to give you rabies?

In the U.S., raccoons, bats, skunks, and foxes are the animals most likely to have rabies, with bats being the most common source of human infection, followed by raccoons as the primary wild animal reservoir. Globally, dogs are the main source of human rabies, but these terrestrial wild animals are the primary concern in North America, with coyotes also being significant carriers.

Do I need a rabies shot if there was a bat in my house?

Yes, you likely need a rabies shot (post-exposure prophylaxis or PEP) if a bat was in your house, especially if anyone was sleeping, a child, or an impaired person was present, or if there was any direct contact (bite, scratch, even waking up with it in the room), because bat bites can be tiny and missed; contact your health department and doctor immediately to arrange for the bat to be tested and to start PEP if exposure is suspected. 

What is the 10 day rule for rabies?

The 10-day observation period for a biting dog, cat, or ferret is a standard public health practice to determine rabies risk: if the animal remains healthy for 10 days after biting someone, it wasn't shedding the rabies virus in its saliva at the time of the bite, meaning the exposed person usually doesn't need rabies post-exposure shots (PEP). This quarantine ensures the animal is available for monitoring, preventing unnecessary euthanasia for brain testing and avoiding expensive PEP for the bite victim if the animal stays healthy.
 

Can we kiss a person who is taking the rabies vaccine?

No, patients who are undergoing preventative vaccination against rabies are not able to transmit the virus to others. The vaccine does not contain live virus but rather a killed form of the virus and is non-infectious.

Are rabies shots given in the belly button?

No, the rabies vaccine has not been given in the stomach since the 1980s. For adults, it should only be given in the deltoid muscle of the upper arm (administration to the gluteal area is NOT recommended, as studies have shown this can result in a less effective immune response).

What is the deadliest virus on Earth?

Using the “case fatality rate” metric to determine what virus is the deadliest, rabies would likely come out on top. That's because, if an infection becomes symptomatic, rabies is fatal to humans in more than 99 percent of cases. Globally, approximately 59,000 people die from rabies every year.

Has anyone died from rabies in 2025?

Rabies is almost always fatal without postexposure prophylaxis (PEP). What is added by this report? In February 2025, CDC confirmed a fatal rabies case in a patient who had received a transplanted kidney from a deceased donor with undiagnosed rabies.

What is the cost of rabies vaccine?

Rabies vaccine prices vary significantly by species and need: for pets, it's typically $10–$75 per shot at low-cost clinics, but potentially more with exams. For humans, pre-exposure (preventative) shots cost hundreds of dollars ($800–$1,300 for the series), while post-exposure treatment after a bite can reach thousands ($2,500–$7,000 for the full protocol including immune globulin). 

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