What happens if you don't treat Cushing's disease in dogs?

If you don't treat Cushing's disease in dogs, the excess cortisol worsens symptoms like thirst, urination, hunger, and lethargy, severely reducing quality of life, and can lead to life-threatening complications like diabetes, high blood pressure, severe skin infections, pancreatitis, and dangerous blood clots (pulmonary thromboembolism) in the lungs, potentially causing early death. While treatment doesn't always extend lifespan, it significantly improves comfort and manages the severe side effects.
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What is the alternative treatment for Cushing's disease in dogs?

Some have found that melatonin and lignans help manage Cushing's disease in dogs. Melatonin helps regulate hormones and maintain circadian rhythms. Lignans mimic phytoestrogen in the body, which may reduce estrogen production in the adrenal gland.
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Why do dogs get Cushing's?

Cushing's disease (hyperadrenocorticism) in dogs is caused by prolonged exposure to excess cortisol, usually from a benign pituitary tumor (most common), a tumor on an adrenal gland, or prolonged use of steroid medications (iatrogenic Cushing's). The pituitary tumor overstimulates the adrenals, while an adrenal tumor produces cortisol directly; both lead to the body making too much cortisol, causing symptoms like increased thirst, urination, skin issues, and a pot-bellied appearance.
 
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What happens if Cushing's is left untreated in dogs?

Pets with Cushing's disease face an increased risk of developing a host of serious conditions including kidney damage, high blood pressure, blood clots, and diabetes if the condition is left untreated.
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What are the three stages of Cushing's disease in dogs?

Stages of Cushing's Disease in Dogs
  • Stage 1: You may notice that your dog is drinking more water and urinating more frequently.
  • Stage 2: Your dog may be losing some of their fur and noticeably gaining weight.
  • Stage 3: The muscles on your dog may be wasting away and they may have a potbellied appearance.
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Cushings Disease in Dogs: Natural Treatment

Should you limit water for a dog with Cushing's?

You must continually monitor your dog's food and water intake. Both should return to a normal level. Water intake should be less than 1 ounce per pound (66 ml per kilogram) of body weight per day, but do not limit water if your dog needs to drink more.
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What foods lower cortisol levels in dogs?

Blueberries are full of antioxidants that fight oxidative stress – a major contributor to anxiety and inflammation. They also contain vitamin C, which helps regulate cortisol, the body's stress hormone. Offering your dog a few blueberries as a treat is a tasty, low-calorie way to support calmness and brain health.
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Can a dog live with Cushing's disease without medication?

Some dogs with Cushing's disease live without treatment for some time, but tend to be happier and healthier with a better quality of life on medication.
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What does milk thistle do for dogs with cushings?

Milk thistle also aids the flow of bile throughout the liver. Dogs with Cushing's disease frequently have elevated liver enzymes (ALP). Increased circulating cortisol causes steroid hepatopathy, which exacerbates the clinical signs of Cushing's. The recommended dosage is 10mg per pound of body weight per day.
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What do vets prescribe for Cushing's disease?

Trilostane (brand name Vetoryl®) is the drug most used. It works by blocking an enzyme involved in hormone synthesis. Mitotane (brand name Lysodren®) is another option. It destroys adrenal tissue and can be associated with more side effects.
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What causes death in dogs with Cushing's?

Cushing's disease progresses slowly. Without treatment, dogs develop higher risks of high blood pressure; pulmonary thromboembolism, which can result in sudden death; congestive heart failure; neurological symptoms; blindness; and myopathy.
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Are dogs with Cushing's in pain?

Yes, Cushing's disease in dogs can indirectly cause pain through muscle weakness leading to joint issues, mobility problems, and recurrent infections, while rare neurological complications from large tumors can also be painful, but the primary symptoms are excessive thirst/urination, pot-belly, and skin/coat problems, with pain often managed through supportive care and medications like NSAIDs or gabapentin alongside Cushing's treatment.
 
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How much does Cushing's medication cost for dogs?

Cushing's Syndrome is not an inexpensive condition

If everything goes perfectly, starting a 20-pound dog on Trilostane and continuing for one year will cost upwards of $1,750 between testing and medications, and that is if everything goes perfectly. It could be more.
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What is the 7 7 7 rule for dogs?

The "7 7 7 rule" for dogs is a puppy socialization guideline, originally by Pat Hastings, suggesting exposing puppies to 7 different people, 7 different locations, and 7 different surfaces/objects/sounds/challenges (variations exist) by about 7 weeks old to build confidence, resilience, and prevent fear or anxiety as adults. Key experiences include meeting diverse individuals, visiting different places like a vet's office or friend's house, walking on various substrates (grass, tile, carpet), and encountering new objects and gentle challenges (like tunnels or boxes).
 
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What is the number one cause of death in Cushing syndrome?

The main cause of death is cardiovascular disease highlighting the negative impact of cortisol excess on cardiovascular risk factors.
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What is end stage Cushing's in dogs?

The final stages of Cushing's disease in dogs involve severe physical decline, marked by extreme muscle weakness, worsening lethargy, significant hair loss, fragile skin, recurring infections, and often uncontrollable urination and thirst, indicating poor quality of life and advanced organ stress from prolonged high cortisol levels, making comfort and palliative care crucial.
 
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Is walking good for a dog with Cushing's disease?

Cushing's can lead to muscle weakness and reduced energy, but regular exercise is crucial for maintaining weight and mental stimulation. Adapt your dog's activity level based on their condition: Low-impact exercise: Gentle activities, such as short walks, swimming, or controlled play sessions, are beneficial.
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What triggers Cushing's disease in dogs?

Cushing's disease (hyperadrenocorticism) in dogs is caused by prolonged exposure to excess cortisol, usually from a benign pituitary tumor (most common), a tumor on an adrenal gland, or prolonged use of steroid medications (iatrogenic Cushing's). The pituitary tumor overstimulates the adrenals, while an adrenal tumor produces cortisol directly; both lead to the body making too much cortisol, causing symptoms like increased thirst, urination, skin issues, and a pot-bellied appearance.
 
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What's the fastest way to lower cortisol?

To lower cortisol fast, focus on immediate stress reduction with deep breathing, yoga, or spending time in nature, combined with lifestyle shifts like prioritizing 7-9 hours of sleep, eating a balanced diet (whole foods, less sugar/caffeine), getting regular moderate exercise, and nurturing healthy relationships to calm your nervous system.
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What foods should you avoid with Cushing's syndrome?

For Cushing's Syndrome, avoid high-sodium processed foods, sugary drinks, refined carbs, excessive alcohol, and caffeine, as they worsen blood pressure, blood sugar, and weight gain; instead, focus on lean protein, calcium/Vitamin D, fruits, veggies, and whole grains to combat muscle/bone loss and manage metabolic issues.
 
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