Should I give my dog a break from Apoquel?

Apoquel (oclacitinib) can be used safely for long-term daily management or stopped/started as needed for seasonal allergies without tapering. It does not build up in the body, so breaks can be taken, but allergic symptoms, such as itching, will likely recur quickly. Consult your vet before stopping to manage potential flare-ups.
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Can dogs be on Apoquel for life?

Apoquel can be used long term, but it must be monitored with yearly (or every 6 months) blood work at the vet to make sure it is not causing any side affects.
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Can you stop and start Apoquel?

Apoquel-A New Treatment for Allergies

It is safe to stop and start, unlike prednisone that requires a gradual tapering when stopping the medication. Apoquel is safe for long term use all year round, or can be used during a certain season when the pet is suffering from allergies.
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Can a dog just stop taking Apoquel?

Rather, it simply reduces the symptoms of allergies by blocking the immune response. This means that dogs taking Apoquel will need to continue taking the medication to manage their allergies, as stopping the medication will likely result in a recurrence of symptoms.
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Do dogs build a tolerance to Apoquel?

Small Dog Allergies: Apoquel Tolerance and Medication Concerns This breed often faces persistent allergies and medication tolerance affecting treatment efficacy. Apoquel tolerance can reduce its effectiveness in controlling allergic symptoms like itching and inflammation.
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What is Apoquel and Does your Dog Need It? Dr. Dan Explains.

Why is my dog still itchy with Apoquel?

We often see pet's with allergies who take anti-itch medications like Cytopoint, Apoquel, steroids and Atopica, but their itching has not resolved or has gotten worse. Frequently, this is due to a secondary infection caused by an underlying disease.
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What is a safer alternative to Apoquel?

Antihistamines. Antihistamines like Zyrtec (cetirizine), Benadryl (diphenhydramine), or hydroxyzine may be recommended for dogs with mild skin allergies before moving to medications like Apoquel or Atopica. These oral medications work by reducing the body's responsiveness to histamines that cause allergic symptoms.
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Does Apoquel have withdrawal symptoms?

Your dog is not likely to experience any sort of withdrawal symptoms when she gets off of Apoquel, but the likelihood for her allergy symptoms to reappear is high within hours of stopping the Apoquel.
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Why are so many dogs on Apoquel?

Apoquel is a widely used medication designed to control itching and inflammation caused by allergic skin diseases in dogs. It has become a popular treatment option due to its fast-acting nature and ability to provide relief without many of the side effects associated with traditional steroids.
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Is it better to give my dog Apoquel in the morning or at night?

If given once daily, it can be given either morning OR night, depending on when your dog seems most itchy. Ideally, Apoquel® should not be used twice daily over a long period of time, as this may increase the chances for side effects.
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What dogs should not take Apoquel?

Apoquel should not be used in dogs under 12 months of age, lactating dogs, or dogs with pre-existing cancers or serious infections.
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Does Apoquel help with paw licking?

Paw licking often relates to allergies or irritations causing discomfort and repetitive behavior. Paw licking in dogs can indicate allergies, infections, or anxiety. Symptoms include redness, swelling, or hair loss on paws. Apoquel is commonly prescribed to control allergic itching by inhibiting inflammatory pathways.
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Is Zyrtec better than Apoquel?

Zyrtec (cetirizine) is safer than Apoquel (oclacitinib) for general use in humans, as Apoquel is specifically approved for dogs and lacks human safety data, while Zyrtec has a well-established human safety profile with minimal sedative effects.
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Can Apoquel cause kidney damage?

Cat owners should take note if they also have dogs prescribed chewable Apoquel for allergies because the medicine can result in acute kidney injury in felines, NC State Veterinary Hospital doctors say.
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Does Apoquel cause behavior problems in dogs?

Can cause side effects such as excessive drinking and urinating, increased appetite,5 and behavior changes, such as increased anxiety, even when used short term. In a 5-year safety review, the most common individual side effects reported with Apoquel were vomiting, diarrhea, lethargy, anorexia, and bloodwork changes.
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How do I stop giving my dog Apoquel?

You can, however, safely stop Apoquel use without tapering dosage. It can be given with or without food, and your dog's weight will determine the exact dose amount. Apoquel doses are usually between . 04-.
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Can dogs stay on Apoquel indefinitely?

Most commonly, veterinarians recommend that dogs start by taking Apoquel twice daily for 14 days. Your vet may then slowly decrease your dog's dosage for long-term use. The goal is to keep your dog on the lowest effective dosage. Many dogs take the medication for the rest of their lives.
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Can Apoquel be used intermittently?

Flexible Apoquel can be used long term to manage chronic itch, or short term to manage intermittent or seasonal itch. Short courses of Apoquel can help reduce allergic itch associated with conditions such as hot spots or ear infections, whilst these are being treated.
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How to stop dog itching without Apoquel?

Antihistamines. Commonly used to manage mild allergy symptoms in dogs, antihistamines like diphenhydramine or cetirizine can help reduce itching and inflammation caused by allergic reactions. They are available over the counter but should be used under veterinary guidance to ensure proper dosage and safety.
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Is CBD better than Apoquel?

Apoquel is great for fast relief, but can raise concerns about immune suppression and long-term risks. CBD takes a more natural route, aiming to support overall balance without shutting down the immune system. Some pet parents combine CBD with Apoquel to help ease side effects, but only under a vet's guidance.
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When should I avoid giving my dog antihistamines?

Antihistamines are usually safe for dogs but can make some dogs drowsy and others hyperactive. OTC antihistamines may contain other ingredients, such as decongestants, that are not safe for dogs.
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Can Apoquel suddenly stop working?

By far the most common reason why I see Apoquel and Cytopoint either not work or “stop working” is because infections like bacteria and malassezia (yeast) have not been addressed. Make sure to do skin cytology to rule out these infections.
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What are the worst months for dog allergies?

Spring and summer are often the worst months for pet allergies to flare. Signs of contact allergies, atopy and food sensitivities are often seen in pets and may be year-round, with worsening symptoms during warmer months when pollens and other allergens are increased in the environment.
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